KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LDHB
All Species:
40.3
Human Site:
S152
Identified Species:
98.52
UniProt:
P07195
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07195
NP_002291.1
334
36638
S152
T
Y
V
T
W
K
L
S
G
L
P
K
H
R
V
Chimpanzee
Pan troglodytes
A5A6N7
334
36634
S152
T
Y
V
T
W
K
L
S
G
L
P
K
H
R
V
Rhesus Macaque
Macaca mulatta
XP_001085541
364
40066
S182
T
Y
V
T
W
K
L
S
G
L
P
K
H
R
V
Dog
Lupus familis
XP_534868
334
36604
S152
T
Y
V
T
W
K
L
S
G
L
P
K
H
R
V
Cat
Felis silvestris
Mouse
Mus musculus
P16125
334
36554
S152
T
Y
V
T
W
K
L
S
G
L
P
K
H
R
V
Rat
Rattus norvegicus
P42123
334
36594
S152
T
Y
V
T
W
K
L
S
G
L
P
K
H
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001121092
332
36433
S151
T
Y
V
A
W
K
I
S
G
F
P
K
N
R
V
Chicken
Gallus gallus
P00337
333
36300
S151
T
Y
V
T
W
K
L
S
G
L
P
K
H
R
V
Frog
Xenopus laevis
P42119
334
36339
S152
T
Y
V
T
W
K
L
S
G
L
P
Q
H
R
I
Zebra Danio
Brachydanio rerio
Q9PVK4
334
36224
S152
T
Y
V
T
W
K
L
S
G
L
P
K
H
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
91.7
99.4
N.A.
97.9
97.9
N.A.
74.8
90.1
82.9
79.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
91.7
99.6
N.A.
99
99
N.A.
87.7
94.9
92.5
91
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
73.3
100
86.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
90
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
100
0
0
0
0
0
90
0
0
0
% K
% Leu:
0
0
0
0
0
0
90
0
0
90
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% S
% Thr:
100
0
0
90
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
90
% V
% Trp:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _